Roy Baynes is Senior Vice President and Head, Global Clinical Development and Chief Medical Officer at Merck Sharp & Dohme (MSD). He was previously Senior Vice President of Oncology, Inflammation and Respiratory Therapeutics at Gilead Sciences and prior to that was Vice President Global Clinical Development and Therapeutic Area (TA) Head for Hematology / Oncology, at Amgen Inc. He graduated as a Medical Doctor and obtained a Master of Medicine and Doctor of Philosophy from the University of the Witwatersrand, Johannesburg, South Africa. He has had a long and distinguished career in the haematology-oncology-and stem cell transplantation fields, including drug development, basic research, clinical practice, clinical research, teaching and administration. He is a member of many international societies, including the American Society of Hematology (ASH) and the American Society of Clinical Oncology (ASCO), and has authored some 150 publications. He has been recurrently named among America’s top physicians. Before joining Amgen in 2002, he was the Charles Martin Professor of Cancer Research at the Barbara Ann Karmanos Cancer Institute, an NCI designated Comprehensive Cancer Center, at Wayne State University, Detroit, Michigan, USA.
Shailendra Singh (Shelly) is Chief Operating Officer of MnM and a member of its board. He focuses on global sales and client services functions, as well as commercial optimization at MarketsandMarkets. He has years of expe¬rience in global delivery and outsourcing sector in the IT/ Consulting/Analytics/Big Data sectors. Prior to MnM, he was leading the global sales, client services and commercial ef¬fectiveness functions for Mu Sigma, a unicorn company and a leading global provider of Decision Sciences and Big Data analytics solutions.
Sewell group research is focused around T-cell ligands and the receptors that recognise them during infection, autoimmune disease, transplant rejection and cancer immunotherapy. The alpha-beta TCR can exploit the MHC class I presentation pathway to target any cell based on its expression of any protein in vivo, thereby accessing a far greater range of targets than are accessible to monoclonal antibodies. Our newer studies indicate that alpha-beta and gamma-delta TCRs can target neoplasms by other, novel mechanisms. We aim to exploit these findings to generate new, broad-spectrum cancer therapeutics.
Scott K. Durum PhD trained at Oak Ridge, National Jewish Denver and Yale before coming to the National Cancer Institute, National Institutes of Health where he is chief of the Section of Cytokines and Immunity. His lab has studied the role of cytokines in the immune system, with a long interest in the IL-7 pathway which is essential for T lymphocyte development and survival. His lab together with collaborators found gain-of-function mutations in the IL-7 receptor that drive acute lymphoblastic leukemia, the most common cancer in children. They are currently studying the mechanism of leukemogenesis and developing therapeutics to target the pathway. He also plays in NIH’s band, the Affordable Rock n Roll Act.
Ian Pike is the Chief Scientific Officer at Proteome Sciences and has 30 years’ experience working in the diagnostics and biotechnology sectors. Having gained a PhD in Medical Microbiology, he joined Welcome Diagnostics as a research group leader and spent 8 years working on new diagnostic assays, particularly for hepatitis. In December 1999, he joined the Technology Transfer Office of the UK Medical Research Council with responsibility for patents and commercialization of a wide portfolio of technologies related to the biomedical sector. Ian also worked for Cancer Research Ventures managing intellectual property and performing business development activities in Europe and the USA. Since joining Proteome Sciences in 2002 he has held a number of roles covering intellectual property management, business development, operational management and is now focused on leading the Company’s scientific strategy to offer clients a flexible, high quality service.