{"id":330,"date":"2019-07-15T14:43:29","date_gmt":"2019-07-15T14:43:29","guid":{"rendered":"http:\/\/events.marketsandmarkets.com\/blog\/?p=330"},"modified":"2019-07-15T14:45:14","modified_gmt":"2019-07-15T14:45:14","slug":"a-study-identifies-autoimmune-disease-to-be-linked-with-testicular-cancer","status":"publish","type":"post","link":"https:\/\/events.marketsandmarkets.com\/blognew\/a-study-identifies-autoimmune-disease-to-be-linked-with-testicular-cancer\/","title":{"rendered":"A Study Identifies Autoimmune Disease to be Linked with Testicular Cancer"},"content":{"rendered":"\n<p>Washington D.C. [USA]: According\nto the Scientists, an&nbsp;autoimmune disease looks to be linked with\ntesticular cancer that affects men. Known to us as <em>&#8216;testicular\ncancer-associated paraneoplastic encephalitis&#8217;<\/em>, it is the reason behind any\nserious neurological symptoms found in men. They lose control of the limbs,\nspeech and eye&nbsp;movements progressively.<\/p>\n\n\n\n<p>The autoimmune disease starts\nwith a testicular tumor, which seems to be the reason behind the immune system\nattacking the brain. Affected men find themselves undiagnosed or misdiagnosed\noften and relevant treatment is delayed.<\/p>\n\n\n\n<p>In a study that was published in\nthe &#8216;New England Journal of Medicine&#8217;, they have identified a remarkably unique\nand specific biomarker&nbsp;for the disease with the use of a technology\nvariation of &#8220;programmable phage display&#8221;. Their refined version\nlinked to this technology screens above 700,000 autoantibody\ntargets&nbsp;simultaneously across all human proteins.<\/p>\n\n\n\n<p>The researchers, with the use of\nthis powerful tool, have evaluated cerebrospinal fluid from a 37-year-old guy\nwho had testicular cancer history and symptoms of debilitating neurological,\nwhich included imbalance, vertigo, and slurred speech. According to the identification\nby the enhanced phage technology, autoantibodies target Kelch-like protein 11\n(KLHL11), which can be found in the testes along with the brain&nbsp;parts.<\/p>\n\n\n\n<p>Moreover, these results have been\ncorrelated and validated with more patient samples gotten from the Mayo Clinic.\nApart from identifying the reason for this mysterious neurological disease,\nthese results are pointing the way to the use of this protein biomarker as a\ntest of diagnostic for men using the testicular cancer-associated\nparaneoplastic encephalitis.&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Washington D.C. [USA]: According to the Scientists, an&nbsp;autoimmune disease looks to be linked with testicular cancer that affects men. Known to us as &#8216;testicular cancer-associated paraneoplastic encephalitis&#8217;, it is the reason behind any serious neurological symptoms found in men. They lose control of the limbs, speech and eye&nbsp;movements progressively. The autoimmune disease starts with a [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":333,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_mi_skip_tracking":false},"categories":[1],"tags":[118,120,119,15,124,122,123,125,121],"_links":{"self":[{"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/posts\/330"}],"collection":[{"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/comments?post=330"}],"version-history":[{"count":1,"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/posts\/330\/revisions"}],"predecessor-version":[{"id":332,"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/posts\/330\/revisions\/332"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/media\/333"}],"wp:attachment":[{"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/media?parent=330"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/categories?post=330"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/events.marketsandmarkets.com\/blognew\/wp-json\/wp\/v2\/tags?post=330"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}